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师资力量
植物病理学系
孙文献
发布日期:2012-04-24 浏览次数: 字号:[ ]

基本信息

姓名:

孙文献

性别:

系别:

植物病理学系

职称:

教授 博士生导师

学位:

博士

Email

wxs@cau.edu.cn

办公电话:

010-62733532

工作经历

1995.08-1998.12 南京农业大学农学系细胞遗传研究所 助教/讲师

2004.01-2008.10 威斯康星大学 植物病理系 博士后

2008.11至今 中国农业大学教授

 

教育经历

1988.09-1992.07 南京农业大学农学系 农学专业 学士

1992.09-1995.07 南京农业大学农学系作物 遗传育种专业 硕士

1999.01-2003.12 美国俄亥俄大学生物学系 分子细胞生物学 博士

 

学术兼职

2022年至今 中国植物病理学会副理事长,秘书长

2021年至今 国家水稻产业体系岗位科学家

2018年至今 Phytopathology Research》资深编委

2017年至今 全国农业专业学位研究生教育指导委员会资源利用与植物保护领域分委员会副组长

2014年至今 第七、八届国务院学位委员会植物保护学科评议组成员

2014年至今 中国植物生理与植物分子生物学学会“植物-微生物分子互作”专业委员会委员

2011年至今 《植物病理学报》副主编

2010年至今 Frontiers in Plant Physiology》编委

2010-2022 中国植物病理学会副秘书长,常务理事(2014-2022

2007至今 国际分子植物与微生物互作学会成员

2002至今 The Plant Cell, Nature Communications, PLoS Pathogens, Molecular Plant Pathology, Molecular Plant-Microbe Interactions20多种国际学术期刊审稿

 

教学工作

《普通植物病理学》普通高等教育农业农村部“十三五”规划教材、全国高等农林院校“十三五”规划教材,副主编

《普通植物病理学实验与实习指导》普通高等教育农业农村部“十三五”规划教材、全国高等农林院校“十三五”规划教材,副主编

 

研究方向

植物基本防卫反应及非寄主抗性的分子机理

植物与病原菌的分子互作

植物病原细菌的毒性与致病力的分子基础

植物病害生物防治的分子机理

水稻抗病性遗传

 

科研项目

1.海南省崖州湾种子实验室科技计划项目课题,2022.11-2025.12,主持

2.国家自然科学基金重大项目课题(32293241),病原真菌致病的分子机制,2023.1-2027.12,主持

3.北京市财政专项项目(BJXCZX20221229)农业微生物功能制剂创制与落地平谷产业化开发(第一期),主持

4.北京市自然科学基金重点项目(6181001),稻曲病菌中稻曲菌素的合成调控机制及其毒性研究,2018.1-2021.12,主持

5.国家自然科学基金面上项目(31770140),细菌性条斑病菌效应蛋白XopE35抑制水稻免疫的分子机理,2018.1-2021.12,主持

6.国家自然科学基金重点项目 (31630064),稻曲病菌致病关键效应蛋白的鉴定及其毒性功能的分子机理,2017.1-2021.12,主持

7.国家自然科学基金面上项目 (31471728),稻曲病菌中稻曲菌素与黑粉菌素合成基因的鉴定及功能分析,2015.1-2018.12,主持

8.农业部公益性行业专项(20130315)作物细菌性病害防控技术研究与示范,2013.1-2017.12,任务主持

9.国家863计划项目(2012AA100703),农林有害生物分子生态调控技术研究,2012.1-2015.12,参与

10.国家科技支撑计划(2012BAD19B03)课题名称:水稻重大病虫害防控技术研究与集成示范,子课题名称,水稻抗病性研究及北方稻区技术集成示范, 2012.1-2016.12,子课题主持

11.国家973计划项目(2011CB100700)植物免疫机制与作物抗病分子设计的重大基础理论,2011.1-2015.10,参与

12.国家自然科学基金面上项目(30971893),白叶枯菌与细菌性条斑菌鞭毛蛋白诱导水稻防卫反应的研究,2010.1-2012.12,主持.

13.教育部博士点基金(20090008110021),水稻OsFLS2对白叶枯菌与细菌性条斑菌鞭毛蛋白识别能力的研究,2010.1-2012.12,主持

14.教育部留学回国人员启动基金,病原菌相关的分子模式(PAMP)诱导的基本防卫反应在水稻抗病育种中的应用,2010.1-2012.12,主持

15.教育部新世纪优秀人才支持计划,NCET-09-0736,新世纪优秀人才,2010.1-2012.12,主持

16.转基因重大专项2012ZX08009003, 小麦抗赤霉病基因的克隆与功能验证,2012.1- 2015.12,参加

17.农业部公益性行业专项(200903039-6)子课题,稻曲病控制技术的研究,起止时间:2009.6-2013.12,子课题主持

18.转基因重大专项(2009ZX08010-004B),2009.6-2010.12,主持

 

代表性论文

*通讯作者,#第一作者)

主要代表性论文:

1. Baohui Mou, Guosheng Zhao, Jiyang Wang, Shanzhi Wang, Feng He, Yuese Ning, Dayong Li, Xinhang Zheng, Fuhao Cui, Fang Xue, Shiyong Zhang, Wenxian Sun*. (2023). The OsCPK17-OsPUB12-OsRLCK176 module regulates immune homeostasis in rice. The Plant Cell.

2. Siwen Yu, Pengwei Liu, Jiyang Wang, Dayong Li*, Dan Zhao, Cui Yang, Dongyu Shi and Wenxian Sun*. (2023). Molecular mechanisms of Ustilaginoidea virens pathogenicity and their utilization in disease control. Phytopathology Research, 5:16

3. Xinhang Zheng, Anfei Fang, Shanshan Qiu, Guosheng Zhao, Jiyang Wang, Shanzhi Wang, Junjun Wei, Han Gao, Jiyun Yang, Baohui Mou, Fuhao Cui, Jie Zhang, Jun Liu, Wenxian Sun*. (2022). Ustilaginoidea virens secretes a family of phosphatases that stabilize the negative immune regulator OsMPK6 and suppress plant immunity. The Plant Cell, 34(8), 3088-3109.

4. Jiyun Yang, Nan Zhang, Jiyang Wang, Anfei Fang, Jing Fan, Dayong Li, Yuejiao Li, Shanzhi Wang, Fuhao Cui, Junjie Yu, Yongfeng Liu, Wen-Ming Wang, You-Liang Peng, Sheng Yang He, Wenxian Sun*. (2022). SnRK1A-mediated phosphorylation of a cytosolic ATPase positively regulates rice innate immunity and is inhibited by Ustilaginoidea virens effector SCRE1. New Phytologist. 236(4):1422-1440.

5. Shanshan Qiu, Anfei Fang, Xinhang Zheng, Shanzhi Wang, Jiyang Wang, Jing Fan , Zongtao Sun, Han Gao, Jiyun Yang, Qingtao Zeng, Fuhao Cui, Wen-Ming Wang, Jianping Chen and Wenxian Sun*. (2022). Ustilaginoidea virens nuclear effector SCRE4 suppresses rice immunity via inhibiting expression of a positive immune regulator OsARF17. International Journal of Molecular Sciences, 23(18), 10527.

6.Chao Wei, Shanzhi Wang, Pengwei Liu, Shou-Ting Cheng, Guoliang Qian, Shuwei Wang, Ying Fu, Wei Qian, Wenxian Sun*. (2021). The PdeK-PdeR two-component system promotes unipolar localization of FimX and pilus extension in Xanthomonas oryzae pv. oryzicola. Science Signaling, 14(700): eabi9589.

7. Muhammad Tariqjaveed, Abdul Mateen , Shanzhi Wang, Shanshan Qiu, Xinhang Zheng, Jie Zhang, Vijai Bhadauria, Wenxian Sun* . (2021). Versatile effectors of phytopathogenic fungi target host immunity. Journal of Integrative Plant Biology, 63(11):1856-1873.

8. Shanzhi Wang, Shuai Li, Jiyang Wang, Qian Li, Xiu-Fang Xin, Shuang Zhou, Yanping Wang, Dayong Li, Jiaqing Xu, Zhao-Qing Luo, Sheng Yang He, Wenxian Sun*. (2021). A bacterial kinase phosphorylates OSK1 to suppress stomatal immunity in rice. Nature Communications, 12(1):5479.

9. Kang Zhang, Zaixu Zhao, Ziding Zhang, Yuejiao Li, Shaojie Li, Nan Yao, Tom Hsiang, Wenxian Sun*. (2021). Insights into genomic evolution from the chromosomal and mitochondrial genomes of Ustilaginoidea virens. Phytopathology Research,3:9.

10. Dayong Li, Shuai Li, Songhong Wei, Wenxian Sun*. (2021). Strategies to manage rice sheath blight: Lessons from interactions between rice and Rhizoctonia solani. Rice,14:21.

11. Yanqing Han, Deqiang Li, Jun Yang, Fu Huang, Hongyan Sheng, Wenxian Sun*. (2020). Mapping quantitative trait loci for disease resistance to false smut of rice. Phytopathology Research,2:20.

12. Wenxian Sun#, Jing Fan#, Anfei Fang, Yuejiao Li, Muhammad Tariqjaveed, Dayong Li, Dongwei Hu, Wen-Ming Wang. (2020). Ustilaginoidea virens: Insights into an Emerging Rice Pathogen. Annu. Rev. Phytopathol, 58:363-385.

13. Nan Zhang, Jiyun Yang, Anfei Fang, Jiyang Wang, Dayong Li , Yuejiao Li ,Shanzhi Wang, Fuhao Cui , Junjie Yu, Yongfeng Liu, Youliang Peng ,Wenxian Sun*. (2020). The essential effector SCRE1 in Ustilaginoidea virens suppresses rice immunity via a small peptide region. Molecular Plant Pathology, 21(4):445-459.

14. Anfei Fang, Han Gao, Nan Zhang, Xinhang Zheng, Shanshan Qiu, Yuejiao Li,

Shuang Zhou, Fuhao Cui and Wenxian Sun*. (2019). A novel effector gene SCRE2 contributes to full virulence of Ustilaginoidea virens to rice. Frontiers in Microbiology, 24:10:845.

15. Yuejiao Li, Ming Wang, Zhaohui Liu, Kang Zhang, Fuhao Cui, Wenxian Sun*. (2019). Towards understanding the biosynthetic pathway for ustilaginoidin mycotoxins in Ustilaginoidea virens. Environ. Microbiol,21(8), 2629–2643

16. Jiyang Wang, Shanzhi Wang, Ke Hu, Jun Yang, Xiaoyun Xin, Wenqing Zhou, Jiangbo Fan, Fuhao Cui, Baohui Mou, Shiyong Zhang, Guo-Liang Wang, Wenxian Sun*. (2018). The kinase OsCPK4 regulates a buffering mechanism that fine-tunes innate immunity. Plant Physiol,176:1835–1849.

17. Fuhao Cui, Wenxian Sun, Xiangpei Kong. (2018). RLCKs Bridge Plant Immune Receptors and MAPK Cascades. Trends Plant Sci, 23:1039-1041.

18. Kang Zhang, Tengjiao Li, Yuejiao Li, Zhi-Gang Li, Tom Hsiang, Ziding Zhang and Wenxian Sun*. (2017). Pathogenicity genes in Ustilaginoidea virens revealed by a predicted protein-protein interaction network. J Proteome Res. 16(3):1193-1206.

19. Lijuan Liu, Yanping Wang, Fuhao Cui, Anfei Fang, Shanzhi Wang, Jiyang Wang, Chao Wei, Shuai Li and Wenxian Sun*. (2017). The type III effector AvrXccB in Xanthomonas campestris pv. campestris targets putative methyltransferases and suppresses innate immunity in Arabidopsis. Mol Plant Pathol. 18(6): 768-782.

20. Anfei Fang, Yanqing Han, Nan Zhang, Min Zhang, Lijuan Liu, Shuai Li, Fen Lu, and Wenxian Sun*. (2016). Identification and characterization of plant cell death–inducing secreted proteins from Ustilaginoidea virens. Mol Plant Microbe Interact, 29(5): 405-416.

21. Chao Wei, Wendi Jiang, Mengran Zhao, Junjie Ling, Xin Zeng, Jun Deng, Dongli Jin, John Maxwell Dow and Wenxian Sun*. (2016). A systematic analysis of the role of GGDEF-EAL domain proteins in virulence and motility in Xanthomonas oryzae pv. oryzicola. Sci Rep, 6: 23769.

22. Yanqing Han, Kang Zhang, Jun Yang, Nan Zhang, Anfei Fang, Yong Zhang, Yongfeng Liu, Zhiyi Chen, Tom Hsiang, Wenxian Sun*. (2015). Differential expression profiling of the early response to Ustilaginoidea virens between false smut resistant and susceptible rice varieties. BMC Genomics, 16:955.

23. Shuai Li, Yanping Wang, Shanzhi Wang, Anfei Fang, Jiyang Wang, Lijuan Liu, Kang Zhang, Yuling Mao and Wenxian Sun*. (2015). The Type III Effector AvrBs2 in Xanthomonas oryzae pv. oryzicola suppresses rice immunity and promotes disease development. Mol Plant Microbe Interact, 28(8): 869-80.

24. Shanzhi Wang, Zhe Sun, Huiqin Wang, Lijuan Liu, Fen Lu, Jun Yang, Min Zhang, Shiyong Zhang, Zejian Guo, Andrew F. Bent, Wenxian Sun*. (2015). Rice FLS2-mediated perception of bacterial flagellins is evaded by Xanthomonas oryzae pvs. oryzae and oryzicola. Molecular Plant, 8:1024-1037.

25. Fen Lu, Huiqin Wang, Shanzhi Wang, Wendi Jiang, Changlin Shan, Bin Li, Jun Yang, Shiyong Zhang, Wenxian Sun*. (2015). Enhancement of innate immune system in monocot rice by transferring the dicotyledonous elongation factor Tu receptor. Journal of Integrative Plant Biology, 57(7): 641-652.

26. Yong Zhang, Kang Zhang, Anfei Fang, Yanqing Han, Jun Yang, Minfeng Xue, Jiandong Bao, Dongwei Hu, Bo Zhou, Xianyun Sun, Shaojie Li, Ming Wen, Nan Yao, Li-Jun Ma, Yongfeng Liu, Min Zhang, Fu Huang, Chaoxi Luo, Ligang Zhou, Jianqiang Li, Zhiyi Chen, Jiankun Miao, Shu Wang, Jinsheng Lai, Jin-Rong Xu, Tom Hsiang, Youliang Peng*, Wenxian Sun*. (2014). Specific adaptation of Ustilaginoidea virens in occupying host florets revealed by comparative and functional genomics, Nature Communications, 5:3849.

27. Yuanbao Zhang, Chao Wei, Wendi Jiang, Lei Wang, Churui Li, Yunyue Wang, Maxwell Dow, Wenxian Sun*. (2013). The HD-GYP domain protein RpfG of Xanthomonas oryzae pv. oryzicola regulates synthesis of extracellular polysaccharides that contribute to biofilm formation and virulence on rice. PLoS ONE, 8(3): e59428.

28. Wenxian Sun#, Yangrong Cao, Kristin Jansen, Bittel, P., Thomas Boller, Andrew F. Bent. (2012). Probing the Arabidopsis flagellin receptor: FLS2-FLS2 association and the contributions of specific domains to signaling function. Plant Cell, 24(3): 1096-1113.

29. Sun, W.#, Liu, L., and Bent, A.F. (2011). Type III secretion–dependent host elicitation and Type III secretion–independent growth within leaves by Xanthomonas campestris pv. campestris. Mol Plant Pathol, 12(8):731-745.

30. Sun, W. #, Dunning, F.M., Pfund, C., Weingarten, R., and Bent, A.F. (2006). Within-species flagellin polymorphism in Xanthomonas campestris pv. campestris and its impact on elicitation of Arabidopsis FLAGELLIN SENSING2-dependent defenses. Plant Cell, 18(3): 764-77.

31. Sun, W. #, Xu, J., Yang, J., Kieliszewski, M.J., and Showalter, A.M. (2005). The lysine-rich arabinogalactan-protein subfamily in Arabidopsis: gene expression, glycoprotein purification and biochemical characterization. Plant and Cell Physiol, 46(6): 975-984.

32. Sun, W. #, Kieliszewski, M.J., and Showalter, A.M. (2004). Overexpression of tomato LeAGP-1 arabinogalactan-protein promotes lateral branching and hampers reproductive development. Plant J, 40(6): 870-81.

33. Sun, W. #, Zhao, Z.D., Hare, M.C., Kieliszewski, M.J., and Showalter, A.M. (2004). Tomato LeAGP-1 is a plasma membrane-bound, glycosylphosphatidylinositol-anchored arabinogalactan-protein. Physiol Plant. 120(2): 319-327.

 

奖励情况

2023 国家神农领军英才

2022 水稻主要病虫害绿色防控技术体系构建及其应用,吉林省科技进步一等奖,排名第一

2022 水稻重大病害稻曲病成灾机制及其绿色防控技术创新与应用,江苏省科学技术进步奖一等奖,排名第二

2022 水稻重大病害稻曲病成灾机制及其绿色防控技术创新与应用,中国植物保护学会科学技术奖一等奖,提名第二

2018 教育部“长江学者奖励计划”特聘教授

2017国家“万人计划”领军人才

2016“植物生物技术导论及实验”课程体系建设探索,中国农业大学教学成果一等奖,第五完成人

2015中国农业大学优秀教师

2015 科技部中青年科技创新领军人才

2009 入选“新世纪优秀人才支持计划”

2015 耐盐高抗水稻新品种盐粳456选育及应用,辽宁省科技进步三等奖,排名第六

20102011 中国农业大学优秀班主任

1999 小麦异染色体系及近缘物种的细胞与分子遗传学研究。中国教育部科学与技术进步一等奖,排名第八

19961997 南京农业大学优秀班主任

 

专利标准

1. 国家发明专利,抗病相关蛋白 OsRLCK176 单位点突变在提高水稻抗病性中的应用,1/7202310063688.7

2. 国家发明专利,水稻核糖核酸酶基因OsRNS4及其编码蛋白与应用,1/7202310063688.7

3. 国家发明专利,一种抗黄单胞菌属病害相关蛋白及其编码基因与应用,1/7202310100491.6

4. 国家发明专利,一种环化磷酸糖酯化合物及其应用,1/7202310100490.1

5. 国家发明专利,一种水稻稻曲病抗性负调控基因及其用途,1/7202211000278.X

6. 国家发明专利,水稻抗病相关基因OsCPK17及其编码蛋白和应用,1/6202211071388.5

7. 国家发明专利,一种从种传和土传媒介中定量检测稻曲病菌的方法,1/6ZL201410259131. 1

 

 

 


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