报告题目：The roles of novel interactions with the principal circadian kinase in the regulation of circadian and cell death pathways

报告人：JEFFREY L. PRICE

Associate Professor, School of Biological Sciences

University of Missouri-Kansas City

报告时间：2017年1月3号下午2点

报告地点：农学楼236

联系人：赵章武 62734225；翟照辉 62733086

报告人简介：

JEFFREY L. PRICE，主要从事果蝇节律调控机理等方面的研究，并在Science, PNAS, Cell, Neurosci, Genetics等国际期刊发表论文百余篇。

Recent Publications:

Means, J.C., Gerdes, B.C., Kaja S., Sumien, N., Payne, A.J. Stark, D.A., Borden, P.K., Price, J.L., Peter Koulen, P., “Caspase 3-Dependent Proteolytic Cleavage of Tau Causes Neurofibrillary Tangles and Results in Cognitive Impairment During Normal Aging,” Neurochem Res 41:2278-2288, 2016.

Means, J.C., Venkatesan, A., Gerdes, B., Fan, J.Y., Bjes. E.S., and Price, J.L., “Drosophila Spaghetti and Doubletime Link the Circadian Clock and Light to Caspases, Apoptosis and Tauopathy,” PLo S Genet 11:e1005171, 2015. * Profiled by a perspective from Patrick Emery.

Fan, J.Y., Means, J.C., Bjes, E.S., Price, J.L., “Drosophila DBT autophosphorylation of its C antagonized by SPAG and involved in UV-induced apoptosis,” Mol Cell Biol 35:2414-2424, 2015.

Venkatesan, A., Fan, J.Y., Nauman, C., and Price, J.L., “A Doubletime Nuclear Localization Signal Mediates an Interaction with Bride of Doubletime to Promote Circadian Function,” Journ Biol Rhythm 30:302-17, 2015

Price, J.L., Fan, J.Y., Keightley, A., Means, J.C., “The Role of Casein Kinase I in the Drosophila Circadian Clock,” Methods Enzymol 551:175-195, 2015.

Price, J.L., “Translational Regulation of the Drosophila Post-translational Circadian Mechanism,” PLo S Genet 10:e1004628, 2014.

Fan, J.Y.,  Agyekum,  B., Venkatesan, A., Hall, D., Keightley, A., Bjes, E.S., Bouyain, S., Price, J.L., “Noncanonical FK506-binding Protein BDBT Binds DBT to Enhance its Circadian Function and Forms Foci at Night,” Neuron 80:984-996, 2013.