报告题目：LUX ARRHYTHMO mediates crosstalk between the circadian clock and defense in Arabidopsis

报告人：Hua Lu, Associate Professor, University of Maryland, USA

时间：2017年8月17日上午9:30-11:00

地点：西校区生命科学大楼3019会议室

联系人：孙文献  崔福浩，电话：6273532/3018

Professional Interests

Pathogen-induced plant diseases are among the greatest deterrents to agriculture worldwide. Properly regulated defense signaling networks are critical for the fitness of plants. However, it remains challenging to identify which genes regulate plant innate immunity, decipher how these genes affect antimicrobial activities, and determine how the defense regulatory networks are coordinated.

We exploit the powerful model system Arabidopsis thaliana in our investigations of mechanisms of plant innate immunity. Arabidopsis is a small herbaceous plant that can be easily grown within limited space. It has a short life cycle and extremely well characterized genetics. In addition, Arabidopsis has a relatively small, fully sequenced genome, and can be easily manipulated at the physiological, genetic and molecular levels. As all higher plants are believed to share similar innate immunity, knowledge on defense mechanisms obtained from Arabidopsis can be readily applied to other plants and enable us to better control diseases in agriculturally important crops.

Recent Publications

Hua Lu, Jean T. Greenberg, and Loreto Holuigue (2016). Editorial: salicylic acid signaling networks. Front Plant Sci 7, 238.

Safae Hamdoun, Chong Zhang, Manroop Gill, Narender Kumar, Michelle Churchman, John C. Larkin, Ashley Kwon, and Hua Lu (2016). Differential roles of two homologous cyclin-dependent kinase inhibitor genes in regulating cell cycle and innate immunity in Arabidopsis. Plant Physiol 170, 515-527.

Guoying Wang*, Chong Zhang*, Stephanie Battle, and Hua Lu (2014) The phosphate transporter PHT4;1 is a salicylic acid regulator likely controlled by the circadian clock protein CCA1. Front. Plant Sci., doi: 10.3389/fpls.2014.00701.

Safae Hamdoun, Yi Liu, Manroop Gill, Nan Yao, and Hua Lu (2013) Dynamics of defense responses and cell fate change during Arabidopsis-Pseudomonas syringae interactions. PLoS ONE 8(12): e83219. doi: 10.1371/journal.pone.0083219.

Wang Xu, Ross Sager, Weier Cui, Chong Zhang, Hua Lu, and Jung-Youn Lee (2013) Salicylic acid represses cell-to-cell communication during innate immune responses in Arabidopsis. Pant Cell.

Chong Zhang, Qiguang Xie, Gina Ng, Ryan G. Anderson, Nick Seitz, Thomas Peterson, C. Robertson McClung, John M. McDowell, Dongdong Kong, June M. Kwak, and Hua Lu (2013) Crosstalk between the circadian clock and innate immunity in Arabidopsis. PLoS Pathogens 9: e1003370. (Selected as the top featured research)

Hua Lu, Chong Zhang, Ute Albrecht, Rena shimizu, Guanfeng Wang, Kim Bowman (2013) Overexpression of a citrus NDR1 ortholog increases disease resistance in Arabidopsis. Frontiers in Plant Science 4 (157).