报告题目：Regulation of phosphoribosyl ubiquitination by factors from pathogen and host cells

报告人：Luo Zhao-Qing, Professor, Department of Biological Sciences, Purdue University

时间：2019年7月28日（周日）上午10:00-11:00

地点：新植保楼3060A会议室

Recent publications

Gan N, Nakayasu ES, Hollenbeck PJ, Luo Z-Q, Legionella pneumophila inhibits immune signaling via MavC-mediated transglutaminase-induced ubiquitination of UBE2N, Nature Microbiology 2019; 4:134-143

Qiu J, Z.-Q. Luo Legionella and Coxiella effectors: Strength in Diversity and Activity. Nature Reviews Microbiology. 2017 July 17 doi:10.1038/nrmicro.2017.67 [Epub ahead of print] PubMed PMID: 28713154

Qiu J, Yu K, Fei X, Liu Y, Nakayasu ES, Piehowski PD, Shaw JB, Puvar K, Das C, Liu X, Luo ZQ. A unique deubiquitinase that deconjugates phosphoribosyl-linked protein ubiquitination. Cell Res. 2017 May 12. doi:10.1038/cr.2017.66. [Epub ahead of print] PubMed PMID: 28497808

Liu Y, Zhu W, Tan Y, Nakayasu ES, Staiger CJ, Luo ZQ. A Legionella Effector Disrupts Host Cytoskeletal Structure by Cleaving Actin. PLoS Pathog. 2017;13(1):e1006186. PMID: 28129393

Qiu J, Sheedlo MJ, Yu K, Tan, Y, Nakayasu ES, Das C, Liu X, Z.-Q. Luo. Ubiquitination independent of E1 and E2 enzymes by bacterial effectors. Nature. 2016;533:120-4 PMID: 27049943

Lu, C, Nakayasu ES, Zhang LQ, and Luo ZQ, Identification of Fic-1 as an enzyme that inhibits bacterial DNA replication by AMPylating GyrB, promoting filament formation. Science Signaling. 2016. 9:ra11.