报告题目：Virus discovery and diversity in Drosophila

报告人：Darren Obbard (Reader)

       英国爱丁堡大学 (The University of Edinburgh)

时间：2021年5月6日 15:00-16:30

地点：腾讯会议ID：825 648 631

联系人：曹川 18710164086

报告人简介:

Darren Obbard博士期间师从牛津大学的John Pannell教授和Stephen Harris教授，于2004年加入爱丁堡大学，先后获得Chancellor's Fellow, Wellcome Trust Research Career Development Fellow资助，2018年成为爱丁堡大学讲师及副教授。近期主要研究方向包括昆虫中的病毒及其多样性，昆虫RNAi通路的进化以及宿主和病毒的相互作用。近五年在Current biology, PLoS Pathogens, PLoS Genetics, Molecular Biology and Evolution等杂志发表文章21篇，引用达1915次，H指数31。

部分代表作：

Obbard DJ, Shi M, Roberts KE, Longdon B, Dennis AB (2020) A new lineage of segmented RNA viruses infecting animals. Virus Evolution 6(1):vez061 [bioRxiv from 21st August 2019]

Palmer WH, Medd NC, Beard PM, Obbard DJ (2018) Isolation of a natural DNA virus of Drosophila melanogaster, and characterisation of host resistance and immune responses. PLOS Pathogens 14(6):e1007050. [bioRxiv from 7th November 2017]

Waldron FM, Stone GS, Obbard DJ, (2018). Metagenomic sequencing suggests a diversity of RNA interference-like responses to viruses across multicellular eukaryotes. PLoS Genet 14(7): e1007533

Webster CL, Waldron FM, Robertson S, Crowson D, Ferrari G, Quintana JF, Brouqui J-M, Bayne EH, Longdon B, Buck AH, Lazzaro BP, Akorli J, Haddrill PR, Obbard DJ, (2015) The discovery, distribution, and evolution of viruses associated with Drosophila melanogaster. PLoS Biology 13(7): e1002210.

Obbard DJ, Maclennan J, Kim K-W, Rambaut A, O'Grady PM, Jiggins FM, (2012) Estimating divergence dates and substitution rates in the Drosophila phylogeny. Molecular Biology and Evolution 29 (11): 3459-3473

Obbard DJ, Gordon KHJ, Buck AH, Jiggins FM (2009) The evolution of RNAi as a defence against viruses and transposable elements. [Review] Philosophical Transactions of the Royal Society Series B 364 99-115.

Obbard DJ, Jiggins FM, Halligan DL, Little TJ (2006). Natural selection drives extremely rapid evolution in antiviral RNAi genes. Current Biology 16: 580-585.